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Solely a restricted HIV subset strikes from mom to youngster, research reveals

Within the transmission of HIV-1 from mom to youngster solely a subset of a mom's viruses infects their infants both in utero or through breastfeeding, and the viruses which are transmitted rely upon whether or not transmission happens throughout being pregnant or by way of breastfeeding, in response to UCLA-led analysis. Mom-to-child transmission of human immunodeficiency virus type1 poses a severe well being menace in growing international locations, and more practical interventions are wanted. Earlier research decided that strains of HIV that infect each adults and infants virtually at all times use the CCR5 co-receptor for an infection and likewise that that an infection is usually established by a single viral variant quite than by a number of variants . Moreover, earlier research have proven a number of the options of the transmitted viruses. The researchers remoted viruses from moms who transmitted HIV to their infants throughout being pregnant and from moms who tran...

New method to assess medication-based HIV prevention proposed

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Antiretroviral drugs -- only one a day -- may also help forestall individuals at excessive danger for HIV an infection from contracting the virus. Credit score: Alec Tributino/The Miriam Hospital One of the crucial promising new approaches to slowing the unfold of HIV is pre-exposure prophylaxis (PrEP), a once-a-day remedy that individuals who haven't got HIV can take to forestall turning into contaminated. However that technique solely works if individuals in danger for contracting HIV turn out to be and stay totally engaged in preventive care and truly take the drugs. In the actual world of medical observe, that has usually proved difficult. In a brand new article within the journal  AIDS , a Brown College-based staff of researchers attracts on their expertise in offering and thoroughly learning PrEP packages to suggest a brand new system for understanding and evaluating how PrEP is applied in medical observe. By viewing the method as a continuum with 9 particul...